Do neurons in the motor cortex encode movement direction? An alternative hypothesis

Abstract

Previous investigations by Georgopoulos et al. of cell activities in the primate motor cortex during the execution of voluntary arm movements have shown that these cells are characterized by tuning properties related to the direction of hand trajectories. Here, it is demonstrated that these findings do not necessarily imply that cortical cells encode spatial features of hand movements and an alternative hypothesis is considered according to which cortical cells encode muscle state variables. It is shown that this hypothesis would lead both to the single-cell activities and to the population behaviors observed by Georgopoulos et al.