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Review
. 2020 Feb;34(1):293-306.
doi: 10.1016/j.hoc.2019.09.010. Epub 2019 Oct 31.

Imaging for Response Assessment in Radiation Oncology: Current and Emerging Techniques

Sonja Stieb  1 , Kendall Kiser  1 , Lisanne van Dijk  1 , Nadia Roxanne Livingstone  1 , Hesham Elhalawani  1 , Baher Elgohari  1 , Brigid McDonald  1 , Juan Ventura  1 , Abdallah Sherif Radwan Mohamed  1 , Clifton David Fuller  2
Affiliations
Review

Imaging for Response Assessment in Radiation Oncology: Current and Emerging Techniques

Sonja Stieb et al. Hematol Oncol Clin North Am. 2020 Feb.

Abstract

Imaging in radiation oncology is essential for the evaluation of treatment response in tumors and organs at risk. This influences further treatment decisions and could possibly be used to adapt therapy. This review article focuses on the currently used imaging modalities for response assessment in radiation oncology and gives an overview of new and promising techniques within this field.

Keywords: CT; Functional imaging; MRI; Organs at risk; PET; Radiation oncology; Response assessment; Tumor.

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Figures

Figure 1:
Figure 1:
Example of a patient with a lung adenocarcinoma metastasis at the left skull base (red arrow). Left: 140 keV DE-CT (window level: −100 – 250 HU), middle: 60 keV DE-CT (window level: −100 – 250 HU), right: Iodine map of DE-CT (window level: −10 – 100 HU).
Figure 2:
Figure 2:
Example of a patient with T2 base of tongue (BOT) tumor and ipsilateral neck lymph node. Left: Treatment plan with BOT tumor delineated in dark green, lymph node in light green and clinical target volume (CTV) in red; middle: PET/CT before treatment (window level for PET: 0.5 – 22 SUV); right: PET/CT 3 months after radiochemotherapy (window level for PET: 0.5 – 22 SUV).
Figure 3:
Figure 3:
54-year old patient with bilateral tonsil cancer stage IVA. Parotid gland structures are highlighted in yellow and pink and were rigidly propagated from T2 image (left) to DIXON (middle) and ADC map (right side).
See this image and copyright information in PMC

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Publication types