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. 1988 Jul;10(4):405-10.
doi: 10.1111/j.1365-3024.1988.tb00230.x.

Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks

J P Opdebeeck  1 , J Y Wong, L A Jackson, C Dobson
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Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks

J P Opdebeeck et al. Parasite Immunol. 1988 Jul.

Abstract

Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination.

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