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. 2019 Oct;71(Suppl 1):542-547.
doi: 10.1007/s12070-018-1394-4. Epub 2018 May 14.

Oncological Outcomes Following Transoral CO2 Laser Microsurgery for T1 Glottic Cancer

Ankur Batra  1 , A Goyal  1 , M Goyal  1 , S Goel  1
Affiliations

Oncological Outcomes Following Transoral CO2 Laser Microsurgery for T1 Glottic Cancer

Ankur Batra et al. Indian J Otolaryngol Head Neck Surg. 2019 Oct.

Abstract

The objective of this study is to analyze oncological outcomes for treatment of Tis and T1 glottic squamous cell carcinoma after transoral laser microsurgery. This study is retrospective analysis of previously untreated, suspected lesion of glottis, staged cT1a and cT1b squamous cell carcinoma in a tertiary care hospital and 53 patients were included in the study. End points for analysis were local control, overall and disease specific survival rates. The local control, ultimate local control with laser alone, 3-year overall survival, 3-year disease specific survival and organ preservation rates were 86.7, 90.5, 92.4, 98.1 and 98.1% respectively. The involvement of anterior commissure did not show any significant impact on local control or survival. TLM is safe and effective treatment of early glottis cancer, associated with less morbidity and a high percentage of local control, survival and organ preservation rates.

Keywords: CO2 laser; Glottis; Laryngeal carcinoma; Squamous cell carcinoma; Transoral laser microsurgery.

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Conflict of interest statement

Conflict of interestAll authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Kaplan–Meier 3 year survival according to tumor stage and for all causes of death
Fig. 2
Fig. 2
Kaplan–Meier 3 year specific survival according to tumor stage
See this image and copyright information in PMC

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References

    1. Mendenhall WM, Werning JW, Hinerman RW, Amdur RJ, Villaret DB. Management of T1-T2 glottic carcinomas. Cancer. 2004;100(9):1786–1792. doi: 10.1002/cncr.20181. - DOI - PubMed
    1. Hartl DM. Evidence-based practice: management of glottic cancer. Otolaryngol Clin North Am. 2012;45:1143–1161. doi: 10.1016/j.otc.2012.06.014. - DOI - PubMed
    1. Strong MS. Laser excision of carcinoma of the larynx. Laryngoscope. 1975;85(8):1286–1289. doi: 10.1288/00005537-197508000-00003. - DOI - PubMed
    1. Strong MS, Jako GJ. Laser surgery in the larynx. Early clinical experience with continuous CO2 laser. Ann Otol Rhinol Laryngol. 1972;81(6):791–798. doi: 10.1177/000348947208100606. - DOI - PubMed
    1. Succo G, Crosetti E, Bertolin A, Lucioni M, Caracciolo A, Panetta V, et al. Benefits and drawbacks of open partial horizontal laryngectomies, Part A: early- to intermediate-stage glottic carcinoma. Head Neck. 2016;38(Suppl 1):E333–E340. doi: 10.1002/hed.23997. - DOI - PubMed

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