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. 2019 Oct;71(Suppl 1):795-797.
doi: 10.1007/s12070-018-1553-7. Epub 2018 Dec 8.

Laryngeal Leiomyosarcoma: A Rare Case

Boon Han Kevin Ng  1 , Ing Ping Tang  1 , G Suhashini  2 , Chiun Kian Chai  3
Affiliations

Laryngeal Leiomyosarcoma: A Rare Case

Boon Han Kevin Ng et al. Indian J Otolaryngol Head Neck Surg. 2019 Oct.

Abstract

Laryngeal leiomyosarcoma is a rare smooth muscle malignancy of the head and neck region. Diagnosis is based on immunohistochemistry. Here we present a case of laryngeal leiomyosarcoma that was diagnosed and treated in our center, focusing on the clinical features, histological diagnosis and management of this rare disease.

Keywords: Laryngeal tumor; Larynx; Leiomyosarcoma.

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Figures

Fig. 1
Fig. 1
Tumour cells that are positive for smooth muscle actin (SMA)
Fig. 2
Fig. 2
The gross specimen of the larynx that was cut open posteriorly to reveal the tumor involving the anterior commissure (white arrow)
Fig. 3
Fig. 3
A low power (H&E 40) image of a circumscribed submucosal tumor composed of intersecting fascicles of haphazardly arranged spindle shaped cells [inset photo: high power image (H&E 400) showing bizarre cells with elongated, pleomorphic nuclei and prominent nucleoli]
See this image and copyright information in PMC

References

    1. Wadhwa AK, Gallivan H, O’Hara BJ, et al. Leiomyosarcoma of the larynx: diagnosis aided by advances in immunohistochemical staining. Ear Nose Throat J. 2000;79:42–46. doi: 10.1177/014556130007900110. - DOI - PubMed
    1. Frank DI. Leiomyosarcoma of the larynx. Arch Otorhinolaryngol. 1941;34:493–500.
    1. Marioni G, Staffieri C, Marino F, Staffieri A. Leiomyosarcoma of the larynx: critical analysis of the diagnostic role played by immnohistochemostry. Am J Otolaryngol Head Neck Med Surg. 2005;26:201–206. - PubMed
    1. Morera Serna E, Fernandez CAP, Jambrina CF, Munoz JR, Gil MAP. Laryngeal leiomyosarcoma. Acta Otorrinolaringol Esp. 2007;58:445–448. doi: 10.1016/S0001-6519(07)74964-6. - DOI - PubMed
    1. Skoulakis, et al. Laryngeal leiomyosarcoma: a case report and review of the literature. Eur Arch Otorhinolaryngol. 2006;263:929–934. doi: 10.1007/s00405-006-0092-0. - DOI - PubMed

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