Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Oct;71(Suppl 1):816-819.
doi: 10.1007/s12070-019-01647-5. Epub 2019 Apr 12.

Ancient Schwannoma: A Rare Intramural Intra-lingual Lesion

T Shashikumar  1 , J S Tejaswini  1 , Shama Bellad  1 , Priti S Hajare  1 , Ramesh S Mudhol  1 , Samanvaya Soni  1 , Kshitija Pathak  1
Affiliations

Ancient Schwannoma: A Rare Intramural Intra-lingual Lesion

T Shashikumar et al. Indian J Otolaryngol Head Neck Surg. 2019 Oct.

Abstract

Ancient schwannoma is an uncommon schwannoma variant which is a benign tumour of Schwann cell origin. It is relatively a rare tumour (25%) in the head and neck region. It is encapsulated and well demarcated from the surrounding tissues. A 35 years old patient in this case presented with painless swelling of the tongue. Trans-oral excision of the intramural lesion was performed. Histopathological and immuno-histochemistry confirmed the diagnosis of schwannoma. This case is of interest on account of the complexity of its diagnosis and the atypical site, that is, intra-mural, of appearance of a schwannoma.

Keywords: Ancient schwannoma; Antoni A, Antoni B bodies; Intramural intra-lingual mass; Tongue swelling.

PubMed Disclaimer

Conflict of interest statement

Conflict of interestAll authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
A 4 × 4 cm solitary, spherical, smooth swelling situated over the dorsum of the tongue
Fig. 2
Fig. 2
T1W STIR image showing a hyperintense lesion with internal cystic changes measuring 3.1 cm cranio-caudal (CC) × 5.0 cm antero-posterior (AP) × 3.2 cm medial-lateral (ML)
Fig. 3
Fig. 3
Showing trans oral excision of lesion was done via a 5 cm incision over the right lateral border. Yellowish encapsulated mass excised en-bloc from within the musculature
Fig. 4
Fig. 4
a Histopathology showing a well encapsulated lesion comprising of spindle shaped cells arranged in fascicles showing spindle to ovoid nuclei and few bizarre nuclei with few hypo cellular areas and sparse mitotic activity and Antoni Type A and Type B cells with Verocay bodies with hyalinised vessels. b Immuno-histochemistry showing S-100 positive. c Vimentin markers positive
Fig. 5
Fig. 5
On post—op 2 months follow-up
See this image and copyright information in PMC

References

    1. Enzinger FM, Weiss SW. Soft tissue tumors. 3. St Louis: Mosby-Year Book Inc.; 1995. pp. 821–888.
    1. Karaca CT, Habesoglu TE, Naiboglu B, Habesoglu M, Oysu C, Egeli E, Tosun I. Schwannoma of the tongue in a child. Am J Otolaryngol. 2009;31:46–48. doi: 10.1016/j.amjoto.2008.09.010. - DOI - PubMed
    1. Jones JA, McWilliam LJ. Intraoral neurilemmoma (schwannoma): an unusual palatal swelling. Oral Surg Oral Med Oral Pathol. 1987;63(3):351–353. doi: 10.1016/0030-4220(87)90203-9. - DOI - PubMed
    1. Wayne Lollar K, Pollak N, Daniel Liess B, Miick R, Zitsch R., III Schwannoma of the hard palate. Am J Otolaryngol. 2010;31:139–140. doi: 10.1016/j.amjoto.2008.11.009. - DOI - PubMed
    1. Moreno-García C, Pons-García MA, González-García R, Monje-Gil F. Schwannoma of tongue. J Maxillofac Oral Surg. 2014;13(2):217–221. doi: 10.1007/s12663-010-0101-0. - DOI - PMC - PubMed

LinkOut - more resources