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Review
. 2019 Nov 19;21(11):140.
doi: 10.1007/s11886-019-1207-8.

Carcinoid Heart Disease: a Comprehensive Review

Saamir A Hassan  1 , Nicolas L Palaskas  2 , Ali M Agha  2 , Cezar Iliescu  2 , Juan Lopez-Mattei  2 , Christopher Chen  3 , Henry Zheng  3 , Syed Wamique Yusuf  2
Affiliations
Review

Carcinoid Heart Disease: a Comprehensive Review

Saamir A Hassan et al. Curr Cardiol Rep. .

Abstract

Purpose of review: Carcinoid heart disease is a rare disorder that is associated with significant morbidity and mortality. In this review of the literature, we will present current concepts in diagnosis and management of carcinoid heart disease.

Recent findings: Recent expert consensus guidelines highlight the role of echocardiography and screening with NT-proBNP for the evaluation of carcinoid heart disease. Advances in medical therapy along with better surgical outcomes highlight the experience and expertise that has been gained in the treatment of carcinoid heart disease. Carcinoid heart disease occurs in patients with neuroendocrine tumors who have carcinoid syndrome. Serotonin appears to play a central role in the development of carcinoid heart disease. Cardiac biomarkers and multimodality imaging can be used to aid in screening and diagnosis. The mainstay of treatment of carcinoid heart disease is surgery.

Keywords: Carcinoid heart disease; Multimodality imaging.

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