Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Nov;19(11):1141-1146.
doi: 10.1111/ggi.13786.

Multivariate analysis of factors related to the absence of musculoskeletal degenerative disease in middle-aged and older people

Shiro Imagama  1 , Kei Ando  1 , Kazuyoshi Kobayashi  1 , Masaaki Machino  1 , Satoshi Tanaka  1 , Masayoshi Morozumi  1 , Shunsuke Kanbara  1 , Sadayuki Ito  1 , Taro Inoue  1 , Taisuke Seki  1 , Shinya Ishizuka  1 , Hiroaki Nakashima  1 , Naoki Ishiguro  1 , Yukiharu Hasegawa  2
Affiliations

Multivariate analysis of factors related to the absence of musculoskeletal degenerative disease in middle-aged and older people

Shiro Imagama et al. Geriatr Gerontol Int. 2019 Nov.

Abstract

Aim: Musculoskeletal degenerative disease (MSD; osteoporosis, knee arthritis and lumbar spondylosis) decreases the quality of life (QOL) of older people. The objective of the present study was to identify the factors related to the absence of MSD in multivariate logistic regression analysis.

Methods: The participants were 1034 volunteers (444 men, 590 women, mean age 63.5 years) in the Yakumo study. Osteoporosis (percentage of young adult mean ≤70%), knee arthritis (Kellgren-Lawrence grade ≥2), and lumbar spondylosis (Nathan class ≥3) were prospectively examined. Participants were divided into those with and without MSD. Age, sex, body mass index, muscle strength, gait ability, pain, body balance, spinal sagittal alignment, geriatric syndrome (locomotive syndrome, frailty and sarcopenia) and QOL (Short Form Health Survey) were compared between these groups to identify the factors associated with the absence of MSD.

Results: Significantly lower age, body mass index and pain; higher gait speed, grip and back muscle strength; more stable body balance; better sagittal spinal alignment; and lower rates of locomotive syndrome, frailty and sarcopenia were observed in the group without MSD (n = 445, 43%), with significantly better QOL (P < 0.0001). In multivariate logistic regression analysis adjusted for age and sex, lower body mass index (odds ratio [OR] 1.10, P < 0.001), lower spinal inclination (OR 1.08, P < 0.01), higher back muscle strength (OR 1.01, P < 0.05), no locomotive syndrome (OR 1.80, P < 0.05) and good body balance (OR: 1.12, P < 0.05) were significant factors for the absence of MSD.

Conclusions: Factors related to an absence of MSD are also related to good QOL, and should be a focus of health interventions in healthy middle-aged and older people. Geriatr Gerontol Int 2019; 19: 1141-1146.

Keywords: back muscle strength; body balance; body mass index; locomotive syndrome; spinal inclination.

PubMed Disclaimer

References

    1. Beaudart C, Biver E, Bruyere O et al. Quality of life assessment in musculo-skeletal health. Aging Clin Exp Res 2018; 30: 413-418.
    1. Imagama S, Ando K, Kobayashi K et al. Impact of comorbidity rates of lumbar spondylosis, knee osteoarthritis, and osteoporosis on physical QOL and risk factors for poor physical QOL in middle-aged and elderly people. Mod Rheumatol 2019; 29: 1-8.
    1. Kasai T, Hasegawa Y, Imagama S et al. The impact of musculoskeletal diseases on mortality-comparison with internal diseases: a 15-year longitudinal study. J Orthop Sci 2017; 22: 1126-1131.
    1. Tsuboi M, Hasegawa Y, Matsuyama Y, Suzuki S, Suzuki K, Imagama S. Do musculoskeletal degenerative diseases affect mortality and cause of death after 10 years in Japan. J Bone Miner Metab 2011; 29: 217-223.
    1. Imagama S, Ando K, Kobayashi K et al. Musculoskeletal factors and geriatric syndromes related to the absence of musculoskeletal degenerative disease in elderly people aged over 70 years old. BioMed Research International in press. 2019. Epub ahead of print.

LinkOut - more resources