T Cell Metabolism in a State of Flux
- PMID: 31747577
- DOI: 10.1016/j.immuni.2019.10.012
T Cell Metabolism in a State of Flux
Abstract
Our knowledge of T cell metabolism relies primarily on studies performed in vitro that may not fully recapitulate physiological conditions in vivo. In this issue of Immunity, Ma et al. find that the in vivo environment dictates the metabolic phenotype of effector CD8+ T cells-particularly their glucose utilization.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8+ T Cells.Immunity. 2019 Nov 19;51(5):856-870.e5. doi: 10.1016/j.immuni.2019.09.003. Epub 2019 Oct 10. Immunity. 2019. PMID: 31747582
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