Papillary Fibroelastoma
- PMID: 31751019
- Bookshelf ID: NBK549829
Papillary Fibroelastoma
Excerpt
Primary cardiac tumors are rare entities, and the majority of these are benign. In adults, papillary fibroelastomas (PFEs) and cardiac myxomas are the most common types of primary cardiac tumors. Papillary fibroelastoma is a benign neoplasm. A single large series of 511 patients at Mayo Clinic by Tamin et al. reported PFEs as the most common cardiac tumor . Increasing utilization of advanced imaging techniques such as transesophageal echocardiography (TEE) has led to more frequent identification of intracardiac tumors. The first reported case of PFE was in 1975 as an embolic complication of PFE, leading to myocardial infarction. Since then, papillary fibroelastomas have been identified as a possible etiology of vascular embolism, stroke, and cardiac arrest. Much controversy still exists in the surgical versus medical management of these “benign” tumors, as they are known to lead to downstream embolic complications. This activity will focus on providing the latest literature update on PFEs.
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Conflict of interest statement
Sections
- Continuing Education Activity
- Introduction
- Etiology
- Epidemiology
- Pathophysiology
- Histopathology
- History and Physical
- Evaluation
- Treatment / Management
- Differential Diagnosis
- Surgical Oncology
- Prognosis
- Complications
- Postoperative and Rehabilitation Care
- Consultations
- Deterrence and Patient Education
- Enhancing Healthcare Team Outcomes
- Review Questions
- References
References
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- Tamin SS, Maleszewski JJ, Scott CG, Khan SK, Edwards WD, Bruce CJ, Oh JK, Pellikka PA, Klarich KW. Prognostic and Bioepidemiologic Implications of Papillary Fibroelastomas. J Am Coll Cardiol. 2015 Jun 09;65(22):2420-9. - PubMed
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- Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies. Arch Pathol Lab Med. 1993 Oct;117(10):1027-31. - PubMed
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- Gowda RM, Khan IA, Nair CK, Mehta NJ, Vasavada BC, Sacchi TJ. Cardiac papillary fibroelastoma: a comprehensive analysis of 725 cases. Am Heart J. 2003 Sep;146(3):404-10. - PubMed
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- Darvishian F, Farmer P. Papillary fibroelastoma of the heart: report of two cases and review of the literature. Ann Clin Lab Sci. 2001 Jul;31(3):291-6. - PubMed