Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Neuroanatomy, Brain Arteries

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Neuroanatomy, Brain Arteries

Richard Yu et al.
Free Books & Documents

Excerpt

The brain receives vascular supply from a network of arteries that anastomose to form the circle of Willis. Because the brain has a constant high metabolic demand and no energy supply of its own, it requires a significant blood supply, consuming 15% of total cardiac output; any blockage of blood flow leads to severe damage and a host of neurological pathologies (see Figure. Diagram of the Brain Blood Circulation).

The brain is supplied by the internal carotid arteries (ICAs), which branch from the common carotid arteries, and the vertebral arteries, which branch from the subclavian. The ICA gives rise to the anterior cerebral artery (ACA) and the middle cerebral artery (MCA). The 2 vertebral arteries unite to form the basilar artery, terminating in the 2 posterior cerebral arteries (PCA). The circle of Willis is the combination of these anterior and posterior divisions (see Image. Outer Surface of the Cerebral Hemisphere).

PubMed Disclaimer

Conflict of interest statement

Disclosure: Richard Yu declares no relevant financial relationships with ineligible companies.

Disclosure: Forshing Lui declares no relevant financial relationships with ineligible companies.

References

    1. Xing CY, Tarumi T, Liu J, Zhang Y, Turner M, Riley J, Tinajero CD, Yuan LJ, Zhang R. Distribution of cardiac output to the brain across the adult lifespan. J Cereb Blood Flow Metab. 2017 Aug;37(8):2848-2856. - PMC - PubMed
    1. Takakuwa T, Koike T, Muranaka T, Uwabe C, Yamada S. Formation of the circle of Willis during human embryonic development. Congenit Anom (Kyoto) 2016 Sep;56(5):233-6. - PubMed
    1. Toma N. Anatomy of the Ophthalmic Artery: Embryological Consideration. Neurol Med Chir (Tokyo) 2016 Oct 15;56(10):585-591. - PMC - PubMed
    1. Djulejić V, Marinković S, Georgievski B, Stijak L, Aksić M, Puškaš L, Milić I. Clinical significance of blood supply to the internal capsule and basal ganglia. J Clin Neurosci. 2016 Mar;25:19-26. - PubMed
    1. Javed K, Das JM. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2023. Aug 8, Neuroanatomy, Anterior Choroidal Arteries. - PubMed

Publication types

LinkOut - more resources