Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Nov 21;18(1):372.
doi: 10.1186/s12936-019-3004-7.

Determinants of uptake of intermittent preventive treatment during pregnancy: a review

Affiliations
Review

Determinants of uptake of intermittent preventive treatment during pregnancy: a review

Elaine Roman et al. Malar J. .

Abstract

Malaria in pregnancy (MiP) contributes to devastating maternal and neonatal outcomes. Coverage of intermittent preventive treatment during pregnancy (IPTp) remains alarmingly low. Data was compiled from MiP programme reviews and performed a literature search on access to and determinants of IPTp. National malaria control and reproductive health (RH) policies may be discordant. Integration may improve coverage. Medication stock-outs are a persistent problem. Quality improvement programmes are often not standardized. Capacity building varies across countries. Community engagement efforts primarily focus on promotion of services. The majority of challenges can be addressed at country level to improve IPTp coverage.

Keywords: Intermittent preventive treatment; Malaria; Pregnancy; Sulfadoxine–pyrimethamine.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Antenatal Care Visits and IPTp3 Uptake. Data derived from the most recent publicly posted Demographic Health Survey, Malaria Indicator Survey, and Multiple Indicator Cluster Survey (MICS). Unless indicated, ANC and IPTp3+ data were derived from the same survey. For the following, the year indicates the survey where IPTp data were derived, and the ANC data were derived from the survey listed: Burkina Faso 2010 DHS, Ghana 2014 DHS, Kenya 2014 DHS, Madagascar 2012 MICS, and Sierra Leone 2013 DHS. The dotted line represents the overall average of IPTp3+ coverage
Fig. 2
Fig. 2
PRISMA flow diagram of studies included in this review. Studies were assessed for eligibility using the PICOTs framework, with Population: Pregnant women, Intervention: IPTp-SP, Outcomes: Access, coverage, feasibility, acceptability, Timing: for peer reviewed literature: May 31, 2016 through May 4, 2018 and for program reviews: no restrictions; Setting: sub-Saharan Africa, Language: English

References

    1. Dellicour S, Tatem AJ, Guerra CA, Snow RW, ter Kuile FO. Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study. PLoS Med. 2010;7:e1000221. doi: 10.1371/journal.pmed.1000221. - DOI - PMC - PubMed
    1. Fleming AF. Tropical obstetrics and gynaecology. 1. Anaemia in pregnancy in tropical Africa. Trans R Soc Trop Med Hyg. 1989;83:441–448. doi: 10.1016/0035-9203(89)90241-1. - DOI - PubMed
    1. Steketee RW, Wirima JJ, Slutsker L, Heymann DL, Breman JG. The problem of malaria and malaria control in pregnancy in sub-Saharan Africa. Am J Trop Med Hyg. 1996;55(Suppl 1):2–7. doi: 10.4269/ajtmh.1996.55.2. - DOI - PubMed
    1. WHO . Strategic framework for malaria prevention and control during pregnancy in African Region, AFR/MAL/04/01. Geneva: World Health Organization; 2004.
    1. Guyatt H, Snow R. Impact of malaria during pregnancy on low birth weight in sub-Saharan Africa. Clin Microbiol Rev. 2004;17:760–769. doi: 10.1128/CMR.17.4.760-769.2004. - DOI - PMC - PubMed

MeSH terms