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Case Reports
. 2020 Jan-Feb;25(1):20-22.
doi: 10.1016/j.rpor.2019.10.009. Epub 2019 Nov 12.

Giant locally advanced and metastatic squamous cell skin carcinoma of head and neck region: case report

Jan Stuk  1   2 , Jaroslav Vanasek  1   2   3 , Karel Odrazka  1   4   5   6 , Martin Dolezel  1   4   7 , Iveta Kolarova  1 , Ales Hlavka  1 , Martina Vitkova  1 , Jan Vodicka  8 , Karel Pokorny  8
Affiliations
Case Reports

Giant locally advanced and metastatic squamous cell skin carcinoma of head and neck region: case report

Jan Stuk et al. Rep Pract Oncol Radiother. 2020 Jan-Feb.

Abstract

Introduction: At the present time, the skin tumors are among the most common cancers. Optimal therapy is based on the extent of the disease and the age of the patient. The need for radiotherapy occurs for inoperable locally advanced tumors and in the event of failure, salvage surgery is applied.

Materials and methods: We provided a case report of an older patient with giant squamous cell skin carcinoma and a review of published articles.

Results: We present a rare case of giant squamous cell skin carcinoma with metastatic satellite tumors that was primarily treated with curative radiotherapy. Five months after radiotherapy, a recurrent tumor was detected at the site of origin and the treatment was completed by salvage surgery. Full remission was achieved for four years.

Conclusion: Despite the seemingly incurable finding it is always necessary to consider radical treatment regardless of the patient´s age. Curative treatment could achieve long term remission in the group of older patients.

Keywords: Head; Neck; Radiotherapy; Recurrent tumor; Skin cancer.

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Figures

Fig. 1
Fig. 1
Giant neck tumor(left) and CT with primary and satellite tumors (right).
Fig. 2
Fig. 2
Local finding one month after radiotherapy.
Fig. 3
Fig. 3
The patient 3 years after treatment.
See this image and copyright information in PMC

References

    1. Lomas A., Leonardi‐Bee J., Bath‐Hextall F. A systematic review of worldwide incidence of nonmelanoma skin cancer. Br J Dermatol. 2012;166(5):1069–1080. - PubMed
    1. Garovich S., Colloca G., Sollena P. Skin cancer epidemics in the elderly as an emerging issue in geriatric oncology. Aging Dis. 2017;8(5):643–661. - PMC - PubMed
    1. Szturz P., Vermorken J.B. Treatment of elderly patients with squamous cell carcinoma of the head and neck. Front Oncol. 2016;6:199. - PMC - PubMed
    1. Amini A., Jones B.L., McDermott J.D. Survival outcomes with concurrent chemoradiation for elderly patients with locally advanced head and neck cancer according to the National Cancer Data Base. Cancer. 2016;122:1533–1543. - PubMed
    1. Apisarnthanarax S., Dhruva N., Ardeshirpour F. Concomitant radiotherapy and chemotherapy for high-risk nonmelanoma skin carcinomas of the head and neck. Int J Surg Oncol. 2011;2011 - PMC - PubMed

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