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Review
. 2020 Jul;45(5):539-543.
doi: 10.1111/ced.14134. Epub 2019 Nov 21.

Lactate dehydrogenase in dermatology practice

A Livesey  1 , F Garty  1 , A R Shipman  1 , K E Shipman  2
Affiliations
Review

Lactate dehydrogenase in dermatology practice

A Livesey et al. Clin Exp Dermatol. 2020 Jul.

Abstract

Lactate dehydrogenase (LDH) is used in dermatology practice, particularly as a prognostic marker for cutaneous lymphoma. LDH is an intracellular enzyme involved in anaerobic glycolysis, and is found at low concentrations in the blood. LDH is produced in every tissue, thus cell damage releases LDH into the circulation, so the causes of elevated LDH levels are multiple. The utility of LDH in dermatology practice is reviewed, alongside current diagnostic and staging guidelines.

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References

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