Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jul 27;71(3):672-676.
doi: 10.1093/cid/ciz1127.

Invasive Mold Infections After Chimeric Antigen Receptor-Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis

Ghady Haidar  1   2 , Kathleen Dorritie  1   3 , Rafic Farah  3 , Tatiana Bogdanovich  2 , M Hong Nguyen  1   2 , Palash Samanta  2
Affiliations
Review

Invasive Mold Infections After Chimeric Antigen Receptor-Modified T-Cell Therapy: A Case Series, Review of the Literature, and Implications for Prophylaxis

Ghady Haidar et al. Clin Infect Dis. .

Abstract

Data on invasive mold infections (IMIs) after chimeric antigen receptor-modified T-cell (CAR-T-cell) therapy are limited. We describe 2 patients with post-CAR-T-cell IMI (Fusarium, Mucorales) and review the published literature. We propose strategies to prevent IMIs in patients, based on the IMI rate and presence of neutropenia or steroid use.

Keywords: CAR-T-cell; fungal infections; neutropenia; prophylaxis; steroids.

PubMed Disclaimer

Comment in

Substances

LinkOut - more resources