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Review
. 2019 Nov 20;8(12):571.
doi: 10.3390/antiox8120571.

Andrographolide, a Natural Antioxidant: An Update

Eugenie Mussard  1 , Annabelle Cesaro  1 , Eric Lespessailles  1   2   3 , Brigitte Legrain  4 , Sabine Berteina-Raboin  5 , Hechmi Toumi  1   2   3
Affiliations
Review

Andrographolide, a Natural Antioxidant: An Update

Eugenie Mussard et al. Antioxidants (Basel). .

Abstract

Traditionally, Andrographis paniculata has been used as an herbal remedy for lung infection treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for a wide range of biological activities such as antioxidant, anti-inflammatory, and anti-cancer properties. This manuscript is a brief review of the antioxidant mechanisms and the regulation of the Nrf2 (nuclear factor (erythroid-derived 2)-like 2) signaling pathway by andrographolide.

Keywords: Andrographis paniculata; Nrf2; andrographolide; oxidative stress.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Andrographis paniculata.
Figure 2
Figure 2
Compounds found in the leaves of Andrographis paniculata.
See this image and copyright information in PMC

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