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Review
. 2020 Jan;29(1):51-62.
doi: 10.1016/j.soc.2019.08.004. Epub 2019 Oct 29.

Precision Medicine and Targeted Therapies in Breast Cancer

Ian Greenwalt  1 , Norah Zaza  2 , Shibandri Das  1 , Benjamin D Li  3
Affiliations
Review

Precision Medicine and Targeted Therapies in Breast Cancer

Ian Greenwalt et al. Surg Oncol Clin N Am. 2020 Jan.

Abstract

Precision medicine and targeted therapies have a long history in the treatment of breast cancer and continue to show promise for further specialized and individualized care for this disease. From the discovery of endocrine and HER2 targeted therapies, to multigene arrays in chemotherapy for more specific patient selection, to radiomics and genetic subtyping, targeted therapies and precision medicine continue to push the management of breast cancer toward more individualized care. This article describes the foundation and future of targeted therapy and precision medicine in breast cancer.

Keywords: Breast cancer; Endocrine therapy; Genomics; HER2; Multigene array; Precision medicine; Radiomics; Targeted therapy.

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