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Practice Guideline
. 2019 Dec 1;117(6):S243-S254.
doi: 10.5546/aap.2019.S243.

[Guideline for diagnosis and treatment of immune thrombocytopenia]

[Article in Spanish]
Affiliations
Free article
Practice Guideline

[Guideline for diagnosis and treatment of immune thrombocytopenia]

[Article in Spanish]
National Hematology Committee, Sociedad Argentina de Pediatría et al. Arch Argent Pediatr. .
Free article

Abstract

Management, outcome, diagnosis, prognosis and treatment of immune thrombocytopenia are controversial. Several guidelines stating different experts' opinions have been published; however, no worldwide consensus regarding the management of the disease has still been reached. This guideline defines diagnostic criteria, states initial laboratory tests, establishes differential diagnosis, develops topics concerning outcome and prognosis, and enumerates available treatments for acute and chronic disease, as well as for management of life-threatening bleeding.

Keywords: idiopathic thrombocytopenic purpura; immune thrombocytopenia; pediatrics; treatment.

Plain language summary

El manejo de la trombocitopenia inmune es motivo de discusión en lo concerniente a evolución, diagnóstico, pronóstico y tratamiento. Se han publicado varias guías que expresan distintas opiniones de expertos, pero no existe aún consenso mundial sobre cuál es el manejo más adecuado de la enfermedad. Esta guía establece los criterios para definir el diagnóstico; detalla el plan de estudios de laboratorio por realizar inicialmente; plantea los distintos diagnósticos diferenciales; desarrolla aspectos relativos a evolución y pronóstico, y enumera los tratamientos disponibles para las formas agudas y las crónicas, así como para el manejo de las emergencias y en algunas situaciones especiales.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

References

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    1. Audia S, Mahévas M, Samson M, Godeau B, et al. Pathogenesis of immune thrombocytopenia. Autoimmun Rev. 2017; 16(6):620-32.

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