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Review
. 2020 Feb:134:428-433.
doi: 10.1016/j.wneu.2019.11.075. Epub 2019 Nov 20.

Adult Atypical Teratoid/Rhabdoid Tumor in the Pineal Region: Case Report and Literature Review

Joana Monteiro  1 , Bruno Santiago  2 , Rui Manilha  2 , Catarina Viegas  2 , Ana Oliveira  3 , Manuel Cunha E Sá  2
Affiliations
Review

Adult Atypical Teratoid/Rhabdoid Tumor in the Pineal Region: Case Report and Literature Review

Joana Monteiro et al. World Neurosurg. 2020 Feb.

Abstract

Background: Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant embryonal central nervous system tumor with a poor prognosis. Its occurrence in the pineal region is extremely rare, with only 6 cases in adults reported so far.

Case description: We report on a puerperal woman with an AT/RT in the pineal region. Total tumor resection was performed. Definitive diagnosis was confirmed by the loss of nuclear INI1/SMARCB1 staining. The patient underwent radiotherapy and chemotherapy with no evidence of recurrence at 31 months after surgery.

Conclusions: This case highlights the importance of immunohistochemistry in the diagnosis of the disease and the importance of an aggressive treatment.

Keywords: Adult; Pineal region; Teratoid rhabdoid tumor.

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