Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Feb;40(1):149-173.
doi: 10.1016/j.iac.2019.09.004. Epub 2019 Nov 6.

Food Allergy Immunotherapy with Adjuvants

Rory E Nicolaides  1 , Christopher P Parrish  1 , J Andrew Bird  2
Affiliations
Review

Food Allergy Immunotherapy with Adjuvants

Rory E Nicolaides et al. Immunol Allergy Clin North Am. 2020 Feb.

Abstract

Treatment of immunoglobulin E-mediated food allergy has traditionally been limited to allergen avoidance and emergency treatment after accidental ingestion. In recent years, significant progress has been made with oral, sublingual, and epicutaneous immunotherapy in the treatment of food allergy; however, these emerging treatment options have important limitations in efficacy, durability of effect, and safety. These limitations have already spurred interest in the development of adjuvant therapies to increase efficacy, produce more durable immunologic changes, and/or reduce treatment-related adverse reactions.

Keywords: Adjuvant therapy; EPIT; Food allergy; Modified allergens; OIT; SLIT.

PubMed Disclaimer