Menin: Expanding and dichotomous roles in cancer
- PMID: 31763368
- PMCID: PMC6855367
- DOI: 10.18632/oncoscience.485
Menin: Expanding and dichotomous roles in cancer
Keywords: EGFR inhibitor; SKP2; colorectal cancer; menin.
Conflict of interest statement
CONFLICTS OF INTEREST The authors declare no potential conflicts of interest.
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References
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- Borkin D, He S, Miao H, Kempinska K, Pollock J, Chase J, Purohit T, Malik B, Zhao T, Wang J, Wen B, Zong H, Jones M, et al. Pharmacologic inhibition of the Menin-MLL interaction blocks progression of MLL leukemia in vivo. Cancer Cell. 2015;27:589–602. doi: 10.1016/j.ccell.2015.02.016. - DOI - PMC - PubMed
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- Katona BW, Glynn RA, Paulosky KE, Feng Z, Davis CI, Ma J, Berry CT, Szigety KM, Matkar S, Liu Y, Wang H, Wu Y, He X, et al. Combined Menin and EGFR Inhibitors Synergize to Suppress Colorectal Cancer via EGFR-Independent and Calcium-Mediated Repression of SKP2 Transcription. Cancer Res. 2019;79:2195–207. doi: 10.1158/0008-5472.CAN-18-2133. - DOI - PMC - PubMed
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