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Review
. 2020 Mar;63(1):134-151.
doi: 10.1097/GRF.0000000000000495.

Intrahepatic Cholestasis of Pregnancy

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Review

Intrahepatic Cholestasis of Pregnancy

Devin D Smith et al. Clin Obstet Gynecol. 2020 Mar.

Abstract

Intrahepatic cholestasis of pregnancy is a common disorder of pregnancy manifested by pruritus and elevated bile acids. The etiology of cholestasis is poorly understood and management is difficult due to the paucity of data regarding its diagnosis, treatment, and related adverse outcomes. In this article, we review the epidemiology, pathophysiology, risk factors, laboratory findings, complications, treatment, management, and current evidence surrounding intrahepatic cholestasis of pregnancy.

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References

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    1. Sjövall K, Sjövall J. Serum bile acid levels in pregnancy with pruritus (bile acids and steroids 158). Clin Chim Acta. 1966;13:207–211.

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