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Meta-Analysis
. 2020 Feb;37(2):229-241.
doi: 10.1111/dme.14190. Epub 2019 Dec 5.

Effectiveness of self-management interventions in young adults with type 1 and 2 diabetes: a systematic review and meta-analysis

S K W Wong  1   2 , H E Smith  1 , J J S Chua  1 , K Griva  1 , E J Cartwright  1 , A J Soong  1 , R Dalan  1   3 , L Tudor Car  1
Affiliations
Meta-Analysis

Effectiveness of self-management interventions in young adults with type 1 and 2 diabetes: a systematic review and meta-analysis

S K W Wong et al. Diabet Med. 2020 Feb.

Abstract

Aim: Diabetes in young adulthood has been associated with poor outcomes. Self-management is fundamental to good diabetes care, and self-management interventions have been found to improve outcomes in older adults. We performed a systematic review and meta-analysis to assess the effectiveness of self-management interventions in young adults (aged 15-39 years) with type 1 or type 2 diabetes.

Methods: We searched five databases and two clinical trial registries from 2003 to February 2019, without language restrictions. We included randomized controlled trials (RCTs) comparing the effectiveness of self-management interventions with usual care or enhanced usual care in young adults. Outcomes of interest included clinical outcomes, psychological health, self-care behaviours, diabetes knowledge and self-efficacy. Pairwise meta-analysis was conducted using a random effects model and quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) criteria. We followed Cochrane gold standard systematic review methodology and reported this systematic review according to PRISMA guidelines. The protocol was registered with PROSEPRO (CRD42018110868).

Results: In total, 13 studies (1002 participants) were included. Meta-analysis showed no difference between self-management interventions and controls in post-intervention HbA1c levels, BMI, depression, diabetes-related distress, overall self-care, diabetes knowledge and self-efficacy. Quality of evidence ranged from very low to moderate due to study limitations, inconsistency and imprecision.

Conclusions: Current self-management interventions did not improve outcomes in young adults with diabetes. Our findings, which contrast with those from systematic reviews in older adults, highlight the need for the development of more effective interventions for young adults with diabetes.

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References

    1. International Diabetes Federation. IDF Diabetes Atlas 2000. Brussels: International Diabetes Federation, 2000. Available at http://www.diabetesatlas.org Last accessed 1 April 2019.
    1. International Diabetes Federation. IDF Diabetes Atlas, 6th edn. Brussels: International Diabetes Federation, 2013. Available at http://www.diabetesatlas.org Last accessed 1 April 2019.
    1. Bryden KS, Dunger DB, Mayou RA, Peveler RC, Neil HAW. Poor prognosis of young adults with type 1 diabetes. Diabetes Care 2003; 26: 1052.
    1. Constantino MI, Molyneaux L, Limacher-Gisler F, Al-Saeed A, Luo C, Wu T et al. Long-term complications and mortality in young-onset diabetes: type 2 diabetes is more hazardous and lethal than type 1 diabetes. Diabetes Care 2013; 36: 3863-3869.
    1. Hillier TA, Pedula KL. Complications in young adults with early-onset type 2 diabetes. Diabetes Care 2003; 26: 2999.

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