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Review
. 2020 Mar;63(1):165-174.
doi: 10.1097/GRF.0000000000000501.

Hepatic Complications in Preeclampsia

Suchitra Chandrasekaran  1 , Rebecca Simon
Affiliations
Review

Hepatic Complications in Preeclampsia

Suchitra Chandrasekaran et al. Clin Obstet Gynecol. 2020 Mar.

Abstract

In cases of preeclampsia with severe features and hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome, hepatic complications portend significant short-term and long-term maternal health implications. In this section, we will discuss the physiology of normal hepatic function in pregnancy, the pathophysiology of the abnormalities noted in hepatic function during the process of preeclampsia development, the diagnosis and management of preeclampsia, imitators of HELLP syndrome, the utility of various biomarkers in the diagnosis and prognosis of the preeclampsia disease spectrum, possible underlying genetic factors predisposing women to developing hepatic abnormalities with preeclampsia, and finally prognosis and management of a subcapsular hematoma.

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