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. 2020 Aug;98(5):e563-e569.
doi: 10.1111/aos.14315. Epub 2019 Nov 26.

Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study

Vincenza Bonfiglio  1 , Elina Ortisi  1 , Davide Scollo  1 , Michele Reibaldi  1 , Andrea Russo  1 , Alessandra Pizzo  1 , Giuseppe Faro  1 , Iacopo Macchi  1 , Matteo Fallico  1 , Mario D Toro  1   2 , Robert Rejdak  2 , Katarzyna Nowomiejska  2 , Lisa Toto  3 , Michele Rinaldi  4 , Salvatore Cillino  5 , Teresio Avitabile  1 , Antonio Longo  1
Affiliations
Free article

Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study

Vincenza Bonfiglio et al. Acta Ophthalmol. 2020 Aug.
Free article

Abstract

Purpose: To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep vessel density (DVD) and their correlation with functional (best-corrected visual acuity, BCVA) and anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RRD) repair.

Method: Patients with RRD eyes, successfully treated with a single pars plana vitrectomy (PPV) with gas tamponade and a minimum 12 months follow-up, were re-examined. Foveal avascular zone (FAZ) area, SVD, DVD and FMT were evaluated by using optical coherence tomography angiography (OCTA) and compared to fellow eye.

Results: Fifty-six patients with macula-on and 37 with macula-off RRD were included in the study. In both groups, no difference in FMT and FAZ area was found compared to fellow eyes. In macula-on RRD eyes, a lower parafoveal DVD (p = 0.001) was detected; FAZ area was related to FMT (p = 0.025), and the postoperative BCVA was correlated with parafoveal DVD (p = 0.010) and FAZ area (p = 0.003). In macula-off RRD eyes, lower parafoveal SDV (p = 0.012), and foveal and parafoveal DVD (p = 0.012 and p < 0.001, respectively) were observed. BCVA was related to FAZ area (p = 0.012), foveal SVD (p = 0.005) and parafoveal DVD (p = 0.010).

Conclusion: Rhegmatogenous retinal detachment eyes successfully treated with PPV had lower vessel density in the superficial and deep retinal plexus compared to fellow healthy eyes; BCVA was related to FAZ area and vessel density.

Keywords: foveal avascular zone; rhegmatogenous retinal detachment; superficial and deep vessel density; vitrectomy.

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References

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