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Comment
. 2019 Nov;18(12):901.
doi: 10.1038/d41573-019-00181-x.

Adding to the senolytic arsenal

Stacey-Lynn Paiva
Comment

Adding to the senolytic arsenal

Stacey-Lynn Paiva. Nat Rev Drug Discov. 2019 Nov.
No abstract available

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Comment on

  • Identification and characterization of Cardiac Glycosides as senolytic compounds.
    Triana-Martínez F, Picallos-Rabina P, Da Silva-Álvarez S, Pietrocola F, Llanos S, Rodilla V, Soprano E, Pedrosa P, Ferreirós A, Barradas M, Hernández-González F, Lalinde M, Prats N, Bernadó C, González P, Gómez M, Ikonomopoulou MP, Fernández-Marcos PJ, García-Caballero T, Del Pino P, Arribas J, Vidal A, González-Barcia M, Serrano M, Loza MI, Domínguez E, Collado M. Triana-Martínez F, et al. Nat Commun. 2019 Oct 21;10(1):4731. doi: 10.1038/s41467-019-12888-x. Nat Commun. 2019. PMID: 31636264 Free PMC article.
  • Cardiac glycosides are broad-spectrum senolytics.
    Guerrero A, Herranz N, Sun B, Wagner V, Gallage S, Guiho R, Wolter K, Pombo J, Irvine EE, Innes AJ, Birch J, Glegola J, Manshaei S, Heide D, Dharmalingam G, Harbig J, Olona A, Behmoaras J, Dauch D, Uren AG, Zender L, Vernia S, Martínez-Barbera JP, Heikenwalder M, Withers DJ, Gil J. Guerrero A, et al. Nat Metab. 2019 Nov;1(11):1074-1088. doi: 10.1038/s42255-019-0122-z. Epub 2019 Oct 21. Nat Metab. 2019. PMID: 31799499 Free PMC article.

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