Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Nov 12:2019:7346013.
doi: 10.1155/2019/7346013. eCollection 2019.

The Impact of Revascularisation on Quality of Life in Chronic Mesenteric Ischemia

J T M Blauw  1   2 , H A M Pastoors  1 , M Brusse-Keizer  3 , R J Beuk  1 , J J Kolkman  4 , R H Geelkerken  1   5 , For The Dutch Mesenteric Ischemia Study Group  6
Affiliations

The Impact of Revascularisation on Quality of Life in Chronic Mesenteric Ischemia

J T M Blauw et al. Can J Gastroenterol Hepatol. .

Abstract

Background: Chronic mesenteric ischemia (CMI) is characterized by long-standing abdominal symptoms due to insufficient mesenteric circulation. Data on the effect of revascularisation on quality of life (QoL) for CMI are scarce. This study is the first to evaluate the impact of revascularisation on quality of life.

Methods: Seventy-nine patients with CMI or acute-on-chronic mesenteric ischemia (AoCMI) underwent an intervention of one or more mesenteric arteries between January 2010 and July 2012. QoL before and after intervention was measured with the EuroQol-5D. Preintervention questionnaires were of standard care. Postintervention data were obtained by resending a questionnaire to the patients between February and May 2013. To investigate the clinical relevance of our findings, the minimal clinically important difference (MCID) was used. Since there is no established MCID for CMI, we used the literature reference MCID of inflammatory bowel syndrome (IBS) of 0.074.

Results: Fifty-five (69.6%) of 79 patients returned their questionnaire and 23 (29.1%) were completely filled out. There was a significant increase of the median EQ-index score from 0.70 to 0.81 (p=0.02) and a significant reduction of symptoms in the domains usual activities (34.4%) and pain/discomfort (32.3%). There was a significant improvement of 17% in overall current health condition (VAS) (p=0.001). The MCID between baseline and postoperative EQ-5D index score was 0.162, indicating a clinically relevant improvement of quality of life after revascularisation.

Conclusion: Quality of life of CMI patients is improved after mesenteric artery revascularisation.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Flowchart of patient inclusion.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Björck M., Koelemay M., Acosta S., et al. Editor’s choice—management of the diseases of mesenteric arteries and veins: clinical practice guidelines of the European society of vascular surgery (ESVS) European Journal of Vascular and Endovascular Surgery. 2017;53(4):460–510. doi: 10.1016/j.ejvs.2017.01.010. - DOI - PubMed
    1. ter Steege R. W. F., Sloterdijk H. S., Geelkerken R. H., Huisman A. B., van der Palen J., Kolkman J. J. Splanchnic artery stenosis and abdominal complaints: clinical history is of limited value in detection of gastrointestinal ischemia. World Journal of Surgery. 2012;36(4):793–799. doi: 10.1007/s00268-012-1485-4. - DOI - PMC - PubMed
    1. Hogendoorn W., Hunink M. G. M., Schlösser F. J. V., Moll F. L., Muhs B. E., Sumpio B. E. A comparison of open and endovascular revascularization for chronic mesenteric ischemia in a clinical decision model. Journal of Vascular Surgery. 2014;60(3):715–725. doi: 10.1016/j.jvs.2014.03.009. - DOI - PubMed
    1. Chandra A., Quinones-Baldrich W. J. Chronic mesenteric ischemia: how to select patients for invasive treatment. Seminars in Vascular Surgery. 2010;23(1):21–28. doi: 10.1053/j.semvascsurg.2009.12.003. - DOI - PubMed
    1. Johnston K. W., Lindsay T. F., Walker P. M., Kalman P. G. Mesenteric arterial bypass grafts: early and late results and suggested surgical approach for chronic and acute mesenteric ischemia. Surgery. 1995;118(1):1–7. doi: 10.1016/s0039-6060(05)80002-9. - DOI - PubMed

LinkOut - more resources