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Case Reports
. 1988 Sep;63(9):1079-80.
doi: 10.1136/adc.63.9.1079.

Leukoencephalopathy after prophylactic radiation for leukaemia in ataxia telangiectasia

J A Eyre  1 , D Gardner-Medwin, G P Summerfield
Affiliations
Case Reports

Leukoencephalopathy after prophylactic radiation for leukaemia in ataxia telangiectasia

J A Eyre et al. Arch Dis Child. 1988 Sep.

Abstract

Children with ataxia telangiectasia have a high probability of developing acute lymphoblastic leukaemia, and have increased sensitivity to chemotherapy and irradiation. We report a 51/2 year old boy who had undiagnosed ataxia telangiectasia when he presented with acute lymphoblastic leukaemia. He subsequently developed a chemoradiation induced leukoencephalopathy after conventional central nervous system prophylaxis.

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