Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jan;16(1):e1905265.
doi: 10.1002/smll.201905265. Epub 2019 Nov 29.

Neodymium-Sensitized Nanoconstructs for Near-Infrared Enabled Photomedicine

Zhongzheng Yu  1 , Wen Kiat Chan  1 , Timothy Thatt Yang Tan  1
Affiliations
Review

Neodymium-Sensitized Nanoconstructs for Near-Infrared Enabled Photomedicine

Zhongzheng Yu et al. Small. 2020 Jan.

Abstract

Neodymium (Nd3+ )-sensitized nanoconstructs have gained increasing attention in recent decades due to their unique properties, especially optical properties. The design of various Nd3+ -sensitized nanosystems is expected to contribute to medical and health applications, due to their advantageous properties such as high penetration depth, excellent photostability, non-photobleaching, low cytotoxicity, etc. However, the low conversion efficiency and potential long-term toxicity of Nd3+ -sensitized nanoconstructs are huge obstacles to their clinical translations. This review article summarizes three energy transfer pathways of all kinds of Nd3+ -sensitized nanoconstructs focusing on the properties of Nd3+ ions and discusses their recent potential applications as near-infrared (NIR) enabled photomedicine. This review article will contribute to the design and fabrication of novel Nd3+ -sensitized nanoconstructs for NIR-enabled photomedicine, aiming for potentially safer and more efficient designs to get closer to clinical usage.

Keywords: Nd 3+-sensitization; energy transfer pathways; nanoconstructs; photomedicine.

PubMed Disclaimer

References

    1. G. Chen, H. Qiu, P. N. Prasad, X. Chen, Chem. Rev. 2014, 114, 5161.
    1. Y. Zhang, W. Wei, G. K. Das, T. T. Y. Tan, J. Photochem. Photobiol., C 2014, 20, 71.
    1. Q. Dou, N. M. Idris, Y. Zhang, Biomaterials 2013, 34, 1722.
    1. a) F. Wang, R. Deng, J. Wang, Q. Wang, Y. Han, H. Zhu, X. Chen, X. Liu, Nat. Mater. 2011, 10, 968;
    1. b) G. Chen, C. Yang, P. N. Prasad, Acc. Chem. Res. 2013, 46, 1474.

Publication types

LinkOut - more resources