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. 2019 Nov 27;20(23):5978.
doi: 10.3390/ijms20235978.

BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities

Piotr Minkiewicz  1 , Anna Iwaniak  1 , Małgorzata Darewicz  1
Affiliations

BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities

Piotr Minkiewicz et al. Int J Mol Sci. .

Abstract

The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified. The addition of new peptides and the introduction of new information about the existing ones (e.g., chemical codes and references to other databases) is in progress. New opportunities include the possibility of annotating peptides containing D-enantiomers of amino acids, batch processing option, converting amino acid sequences into SMILES code, new quantitative parameters characterizing the presence of bioactive fragments in protein sequences, and finding proteinases that release particular peptides.

Keywords: SMILES code; bioactive peptides; chronic diseases; database; foods; nutraceuticals; nutrition; proteolysis.

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Conflict of interest statement

The Authors declare no conflict of interests.

Figures

Figure 1
Figure 1
Scheme of organization of the BIOPEP-UWM database of bioactive peptides.
Figure 2
Figure 2
Scheme of the “enzyme(s) action” tab. Option (see Figure 1) “search for enzyme with given specificity” is not included in the Figure. A screenshot of the menu of this tab is presented in Supplementary Figure S11.
Figure 3
Figure 3
Scheme of the “batch processing” tab action.
Figure 4
Figure 4
Scheme of “find enzyme for peptide release” tab action.
See this image and copyright information in PMC

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