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Review
. 2019 Dec 10;37(52):7610-7622.
doi: 10.1016/j.vaccine.2019.05.030.

Chorioamnionitis: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data

Alisa Kachikis  1 , Linda O Eckert  1 , Christie Walker  1 , Azucena Bardají  2 , Frederick Varricchio  3 , Heather S Lipkind  4 , Khady Diouf  5 , Wan-Ting Huang  6 , Ronald Mataya  7 , Mustapha Bittaye  8 , Clare Cutland  9 , Nansi S Boghossian  10 , Tamala Mallett Moore  11 , Rebecca McCall  12 , Jay King  11 , Shuchita Mundle  13 , Flor M Munoz  14 , Caroline Rouse  15 , Michael Gravett  1 , Lakshmi Katikaneni  16 , Kevin Ault  17 , Nicola P Klein  18 , Drucilla J Roberts  19 , Sonali Kochhar  20 , Nancy Chescheir  21 ; Brighton Collaboration Chorioamnionitis Working Group
Affiliations
Review

Chorioamnionitis: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data

Alisa Kachikis et al. Vaccine. .
No abstract available

Keywords: Adverse event; Amnionitis; Case definition; Chorioamnionitis; Guidelines; Immunization; Intra-amniotic infection.

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Conflict of interest statement

Nicola Klein reports research support from GlaxoSmithKline, Pfizer, Sanofi Pasteur, Merck & Co and Protein Science (now Sanofi Pasteur). Kevin Ault is on several data and safety committees for maternal immunization and drug treatment trials.

Figures

Fig. 1
Fig. 1
Placental anatomy in the context of intra-amniotic infections (See Section 1.3.4c). Reprinted with permission from Goldenberg RL, Hauth JC, Andrews WW. Intrauterine infection and preterm delivery. N Engl J Med. 2000 May 18;342(20):1500–7 .
Fig. 2
Fig. 2
Flow diagram describing pathway for source identification.
Fig. 3
Fig. 3
Definitions synthesized for chorioamnionitis based on the systematic literature review. (Two definitions for clinical chorioamnionitis were developed to correlate with the more specific definition for intraamniotic infection (or “Triple I”) from the NICHD chorioamnionitis workship (Clinical definition A), and with the more sensitive Gibbs criteria for chorioamnioitis (Clinical definition B). Please see Section 1.3.4 for further details.)
Fig. 4
Fig. 4
Case definition for chorioamnionitis with levels 1–3 of certainty.
See this image and copyright information in PMC

References

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