CITRIS-ALI: How statistics were used to obfuscate the true findings

Affiliations

¹ Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, 825 Fair Suite 410, Norfolk, VA 23507, UK. Electronic address: marikpe@evms.edu.
² University Paris 7 Denis Diderot, Cité Sorbonne, Paris, France.

Editorial

Paul E Marik et al. Anaesth Crit Care Pain Med. 2019 Dec.

. 2019 Dec;38(6):575-577.

doi: 10.1016/j.accpm.2019.10.004.

¹ Pulmonary and Critical Care Medicine, Eastern Virginia Medical School, 825 Fair Suite 410, Norfolk, VA 23507, UK. Electronic address: marikpe@evms.edu.
² University Paris 7 Denis Diderot, Cité Sorbonne, Paris, France.

No abstract available

Keywords: ARDS; SOFA score; Statistics; Vitamin C.

Comment on

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.
Fowler AA 3rd, Truwit JD, Hite RD, Morris PE, DeWilde C, Priday A, Fisher B, Thacker LR 2nd, Natarajan R, Brophy DF, Sculthorpe R, Nanchal R, Syed A, Sturgill J, Martin GS, Sevransky J, Kashiouris M, Hamman S, Egan KF, Hastings A, Spencer W, Tench S, Mehkri O, Bindas J, Duggal A, Graf J, Zellner S, Yanny L, McPolin C, Hollrith T, Kramer D, Ojielo C, Damm T, Cassity E, Wieliczko A, Halquist M. Fowler AA 3rd, et al. JAMA. 2019 Oct 1;322(13):1261-1270. doi: 10.1001/jama.2019.11825. JAMA. 2019. PMID: 31573637 Free PMC article. Clinical Trial.