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Case Reports
. 2020 Mar 15;59(6):779-782.
doi: 10.2169/internalmedicine.3244-19. Epub 2019 Nov 29.

Seeding of a Tumor in the Gastric Wall after Endoscopic Ultrasound-guided Fine-needle Aspiration of Solid Pseudopapillary Neoplasm of the Pancreas

Haruomi Yamaguchi  1 , Hiroyuki Morisaka  1 , Katsuhiro Sano  1 , Koji Nagata  2 , Shomei Ryozawa  3 , Kojun Okamoto  4 , Tomoaki Ichikawa  1
Affiliations
Case Reports

Seeding of a Tumor in the Gastric Wall after Endoscopic Ultrasound-guided Fine-needle Aspiration of Solid Pseudopapillary Neoplasm of the Pancreas

Haruomi Yamaguchi et al. Intern Med. .

Abstract

Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is widely used as a first-line procedure for the definitive diagnosis of pancreatic solid tumor. Adverse events associated with the EUS-FNA procedure include acute pancreatitis, bleeding, infection, and duodenal perforation. Rarely, pancreatic tumors disseminate in the peritoneal cavity or seed in the gastric wall via the biopsy needle tract after EUS-FNA. Such seeding has been noted primarily in cases of adenocarcinomas and has not been associated with solid pseudopapillary neoplasm (SPN), a rare and potentially malignant tumor of the pancreas. This is the first report of a case of tumor seeding in the gastric wall after EUS-FNA of pancreatic SPN.

Keywords: endoscopic ultrasound-guided fine-needle aspiration; needle tract seeding; solid pseudopapillary neoplasm.

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Conflict of interest statement

The authors state that they have no Conflict of Interest (COI).

Figures

Figure 1.
Figure 1.
Preoperative abdominal contrast-enhanced computed tomography shows a hypovascular tumor 6 cm in diameter with a cystic or necrotic component in the body of the pancreas.
Figure 2.
Figure 2.
Hematoxylin and Eosin staining (a, ×400) of the tumor of the body of the pancreas shows atypical tumor cells with solid growth that appear as distinct nuclear and cytoplasmic positive staining of beta-catenin on immunostaining (b, ×400)
Figure 3.
Figure 3.
Upper gastrointestinal endoscopy reveals a protruding tumor in the posterior gastric wall.
Figure 4.
Figure 4.
Abdominal contrast-enhanced computed tomography reveals a hypervascular tumor 4 cm in diameter in the posterior gastric wall.
Figure 5.
Figure 5.
Hematoxylin and Eosin staining (a, ×400) of the resected gastric tumor shows atypical tumor cells with a glandular and solid pattern. Tumor cells show distinct nuclear and cytoplasmic positive staining of beta-catenin on immunostaining (b, ×400).
See this image and copyright information in PMC

References

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