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. 2019 Oct 16;11(10):e5920.
doi: 10.7759/cureus.5920.

Risk Factors of Incidental Parathyroidectomy and its Relationship with Hypocalcemia after Thyroidectomy: A Retrospective Study

Affiliations

Risk Factors of Incidental Parathyroidectomy and its Relationship with Hypocalcemia after Thyroidectomy: A Retrospective Study

Erdem Karadeniz et al. Cureus. .

Abstract

Background: The aim of this study was to determine the incidence of incidental parathyroidectomy, the relationship between incidental parathyroidectomy and postoperative hypocalcemia, and risk factors for incidental parathyroidectomy in patients undergoing thyroid surgery.

Methods: The study was conducted by analyzing the records of patients who underwent thyroid surgery in a tertiary university hospital between January 2012 and December 2017 retrospectively. The risk factors of postoperative hypocalcemia were determined by comparing postoperative Ca values with age, sex, preoperative Ca value, dominant nodule diameter, type of surgery, and histopathological examination of the thyroidectomy material. According to the final pathology results, the patients were divided into two groups - the ones with and without incidental parathyroidectomy. The risk factors for incidental parathyroidectomy were determined by comparing the two groups in terms of age, sex, dominant nodule diameter, type of surgery, and histopathological results (malign/benign).

Results: When the risk factors of postoperative hypocalcemia were examined, female gender, age <28.5 years old, low level of preoperative mean Ca value, and total thyroidectomy were found to be critical risk factors (p<0.05). When the risk factors of incidental parathyroidectomy were examined, total thyroidectomy and thyroid malignancy were found to be important risk factors (p<0.05).

Conclusion: Female gender, age<28.5 years old, low level of preoperative Ca value, and total thyroidectomy were associated with postoperative hypocalcemia, but no relationship was found between incidental parathyroidectomy and postoperative hypocalcemia.

Keywords: hypocalcaemia; incidental; parathyroidectomy; thyroidectomy.

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Morbidity of thyroid surgery. Bergamaschi R, Becouarn G, Ronceray J, Arnaud JP. Am J Surg. 1998;176:71–75. - PubMed
    1. Factors related to nerve injury and hypocalcemia in thyroid gland surgery. Prim MP, de Diego JI, Hardisson D, Madero R, Gavilan J. Otolaryngol Head Neck Surg. 2001;124:111–114. - PubMed
    1. Prediction of permanent hypoparathyroidism after total thyroidectomy. Almquist M, Hallgrimsson P, Nordenstrom E, Bergenfelz A. World J Surg. 2014;38:2613–2620. - PubMed
    1. Predictors and risk factors of hypoparathyroidism after total thyroidectomy. Cho JN, Park WS, Min SY. Int J Surg. 2016;34:47–52. - PubMed
    1. Parathyroid risk in total thyroidectomy for bilateral, benign, multinodular goitre: report of 351 surgical cases. Page C, Strunski V. J Laryngol Otol. 2007;121:237–241. - PubMed

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