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Case Reports
. 2019 Dec 1;12(11):e229717.
doi: 10.1136/bcr-2019-229717.

A case of contrast-induced encephalopathy

Affiliations
Case Reports

A case of contrast-induced encephalopathy

Patrick Neilan et al. BMJ Case Rep. .

Abstract

The differential diagnosis of the patient with encephalopathy is broad and remains a common yet challenging problem for critical care physicians. A case is presented of contrast-induced encephalopathy in an 81-year-old man undergoing a left heart catheterisation after receiving iopamidol, a low-osmolar contrast agent. Immediately after receiving contrast, our patient experienced severe headache, agitation, altered mentation and significant skin hypersensitivity. This rare, acute and reversible neurological disturbance can be associated with administration of intra-arterial, osmotic, iodinated contrast. Although uncommon, it is important to recognise the various presentations, risk factors and treatment of this condition.

Keywords: adult intensive care; headache (including migraines); intensive care; neurology; neurology (drugs And Medicines).

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
CT of the patient demonstrating increased density of the falx and tentorium corresponding to recent contrast administration.
Figure 2
Figure 2
MRI of the patient demonstrating age-related changes.

References

    1. Frantz W. Cortical blindness following coronary angiography in a patient with LIMA bypass graft and end stage renal failure. Proceedings of EuroPCR 2006:21–4.
    1. Yu J, Dangas G. Commentary: New insights into the risk factors of contrast-induced encephalopathy. J Endovasc Ther 2011;18:545–6. 10.1583/11-3476C.1 - DOI - PubMed
    1. Guimaraens L, Vivas E, Fonnegra A, et al. . Transient encephalopathy from angiographic contrast: a rare complication in neurointerventional procedures. Cardiovasc Intervent Radiol 2010;33:383–8. 10.1007/s00270-009-9609-4 - DOI - PubMed
    1. Liao MT, Lin TT, Lin LY, et al. . Contrast-Induced Encephalopathy after Percutaneous Coronary Intervention. Acta Cardiol Sin 2013;29:277–80. - PMC - PubMed
    1. Muruve DA, Steinman TI. Contrast-induced encephalopathy and seizures in a patient with chronic renal insufficiency. Clin Nephrol 1996;45:406–9. - PubMed

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