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. 2019 Dec 2;29(23):R1247-R1248.
doi: 10.1016/j.cub.2019.10.056.

Meiosis: How Gambling Chromosomes Beat the Rules

Courtney M Schroeder  1 , Harmit S Malik  2
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Meiosis: How Gambling Chromosomes Beat the Rules

Courtney M Schroeder et al. Curr Biol. .
Free article

Abstract

Selfish centromeres exploit asymmetric female meiosis to drive non-Mendelian segregation in their favor. Using inherent differences in drive propensity between mouse chromosomes, a new study reveals how proteins that modify chromatin states and microtubule stability enable this selfish behavior.

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