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Case Reports
. 1988 Oct 15;35(2):231-5.
doi: 10.1016/0165-4608(88)90245-2.

Granulocytic sarcoma of the small intestine preceding acute myelomonocytic leukemia with abnormal eosinophils and inv(16)

S J Russell  1 , F J Giles, D S Thompson, D J Scanlon, H Walker, J D Richards
Affiliations
Case Reports

Granulocytic sarcoma of the small intestine preceding acute myelomonocytic leukemia with abnormal eosinophils and inv(16)

S J Russell et al. Cancer Genet Cytogenet. .

Abstract

We report a case of preleukemic granulocytic sarcoma of the small intestine preceding the development of acute myelomonocytic leukemia with abnormal eosinophils and inversion of chromosome 16, inv(16)(p13q22). A literature review suggests that this is a recurring cytogenetic-clinicopathologic association and carries a favorable prognosis, especially if treated aggressively with antileukemic therapy at the time of diagnosis.

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