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Review
. 2019 Nov 19:7:481.
doi: 10.3389/fped.2019.00481. eCollection 2019.

Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)

Elie Haddad  1 , Manfred Hoenig  2
Affiliations
Review

Hematopoietic Stem Cell Transplantation for Severe Combined Immunodeficiency (SCID)

Elie Haddad et al. Front Pediatr. .

Abstract

Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between subtypes and the inherent reduced capacity or inablility to reject a graft have to be considered.

Keywords: HSCT; SCID; clinical presentation; hematopoietic stem cell transplantation; infections; severe combined immunodeficiency.

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References

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