Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Mar 1;35(3):544-546.
doi: 10.1093/ndt/gfz244.

Cardiovascular events associate with diabetes status rather than with early basal insulin treatment for the prevention of post-transplantation diabetes mellitus

Affiliations

Cardiovascular events associate with diabetes status rather than with early basal insulin treatment for the prevention of post-transplantation diabetes mellitus

David Topitz et al. Nephrol Dial Transplant. .
No abstract available

PubMed Disclaimer

Figures

FIGURE 1
FIGURE 1
Cardiovascular events throughout 7 years of follow-up in kidney transplant recipients who received early basal insulin therapy versus standard of care (left panel) and in the same cohort of patients, but sorted by normal glucose tolerance (NGT) versus by impaired glucose tolerance (IGT) plus diabetes during three oral glucose tolerance tests performed in the first post-operative year (right panel). Cardiovascular events: myocardial infarction, coronary angioplasty/artery bypass graft surgery, valve replacement, congestive heart failure, peripheral artery disease and stroke. Log-rank test for the basal insulin treatment versus standard-of-care control group: P = 0.84. Log-rank test for non-diabetic versus diabetic plus pre-diabetic patients: P = 0.155.

References

    1. Hecking M, Werzowa J, Haidinger M et al. Novel views on new-onset diabetes after transplantation: development, prevention and treatment. Nephrol Dial Transplant 2013; 28: 550–566 - PMC - PubMed
    1. Jenssen T, Hartmann A. Post-transplant diabetes mellitus in patients with solid organ transplants. Nat Rev Endocrinol 2019; 15: 172–188 - PubMed
    1. Gaynor JJ, Ciancio G, Guerra G et al. Single-centre study of 628 adult, primary kidney transplant recipients showing no unfavourable effect of new-onset diabetes after transplant. Diabetologia 2015; 58: 334–345 - PubMed
    1. Kuo HT, Sampaio MS, Vincenti F et al. Associations of pretransplant diabetes mellitus, new-onset diabetes after transplant, and acute rejection with transplant outcomes: an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) database. Am J Kidney Dis 2010; 56: 1127–1139 - PubMed
    1. Cosio FG, Kudva Y, van der Velde M et al. New onset hyperglycemia and diabetes are associated with increased cardiovascular risk after kidney transplantation. Kidney Int 2005; 67: 2415–2421 - PubMed