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Multicenter Study
. 2020 Jan;188(1):170-173.
doi: 10.1111/bjh.16364. Epub 2019 Dec 6.

Tolerance to arsenic trioxide combined with all-trans-retinoic acid in children with acute promyelocytic leukaemia in France

Emmanuel Garcia Spezza  1 , Benoit Brethon  2 , Arnaud Petit  3 , Franҫoise Mazingue  4 , Virginie Gandemer  5 , Nicolas Boissel  6 , Liana Carausu  7 , Yves Reguerre  1 , Guy Leverger  3 , Stephane Ducassou  8   9
Affiliations
Multicenter Study

Tolerance to arsenic trioxide combined with all-trans-retinoic acid in children with acute promyelocytic leukaemia in France

Emmanuel Garcia Spezza et al. Br J Haematol. 2020 Jan.
No abstract available

Keywords: acute promyelocytic leukaemia; all-trans retinoic acid; arsenic trioxide; children.

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References

    1. Burnett, A.K., Russell, N.H., Hills, R.K., Bowen, D., Kell, J., Knapper, S., Morgan, Y.G., Lok, J., Grech, A., Jones, G. & Khwaja, A. (2015) Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML17): results of a randomised, controlled, phase 3 trial. Lancet Oncology, 16, 1295-1305.
    1. Creutzig, U., Dworzak, M.N., Bochennek, K., Faber, J., Flotho, C., Graf, N., Kontny, U., Rossig, C., Schmid, I., von Stackelberg, A. & Mueller, J.E. (2017) First experience of the AML-Berlin-Frankfurt-Münster group in pediatric patients with standard-risk acute promyelocytic leukemia treated with arsenic trioxide and all-trans retinoid acid. Pediatric Blood Cancer, 64, e26461.
    1. Iland, H.J., Collins, M., Bradstock, K., Supple, S.G., Catalano, A., Hertzberg, M., Browett, P., Grigg, A., Firkin, F., Campbell, L.J. & Hugman, A. (2015) Use of arsenic trioxide in remission induction and consolidation therapy for acute promyelocytic leukaemia in the Australasian Leukaemia and Lymphoma Group (ALLG) APML4 study: a non-randomised phase 2 trial. The Lancet Haematology, 2, 357-366.
    1. Kayser, S., Schlenk, R.F. & Platzbecker, U. (2018) Management of patients with acute promyelocytic leukemia. Leukemia, 32, 1277-1294.
    1. Kutny, M.A., Alonzo, T.A., Gerbing, R.B., Wang, Y.C., Raimondi, S., Hirsch, B.A., Fu, C.H., Meshinchi, S., Gamis, A.S., Feusner, J.H. & Gregory, J.J. Jr (2017) Arsenic trioxide consolidation allows anthracycline dose reduction for pediatric patients with acute promyelocytic leukemia: report from the Children's Oncology Group Phase III historically controlled trial AAML0631. Journal Clinical Oncology, 35, 3021-3029.

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