Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec 2;12(23):3998.
doi: 10.3390/ma12233998.

Mechanical and Functional Properties of a Novel Apatite-Ionomer Cement for Prevention and Remineralization of Dental Caries

Rie Imataki  1 , Yukari Shinonaga  2 , Takako Nishimura  2 , Yoko Abe  2 , Kenji Arita  2
Affiliations

Mechanical and Functional Properties of a Novel Apatite-Ionomer Cement for Prevention and Remineralization of Dental Caries

Rie Imataki et al. Materials (Basel). .

Abstract

Especially in pediatric dentistry, prevention by the control of initial lesions prior to cavitation is very important, and application of a pit and fissure sealant is essential to achieve this. Numerous reports have suggested that resin-based sealants are inferior to sealants based on glass-ionomer cement (GIC), because of GIC's many advantages, such as fluoride ion release properties and its good adhesion to tooth structures. However, the use of GIC is impeded due to its low flexural strength and fracture toughness. In this paper, we developed and characterized an apatite-ionomer cement (AIC) that incorporates hydroxyapatite (HAp) into the GIC; this development was aimed at not only reinforcing the flexural and compressive strength but also improving some functional properties for the creation of the material suitable for sealant. We examined the influence of differences in the compounding conditions of GIC powder, liquid, and HAp on flexural and compressive strengths, fracture toughness, fluoride ion release property, shear bond strength to bovine enamel, surface pH of setting cements, and acid buffer capability. These methods were aimed at elucidating the reaction mechanism of porous spherical-shaped HAp (HApS) in AIC. The following observations were deduced. (1) HAp can improve the mechanical strengths of AIC by strengthening the cement matrix. (2) The functional properties of AIC, such as acid buffer capability, improved by increasing the releasing amounts of various ions including fluoride ions. The novel AIC developed in this study is a clinically effective dental material for prevention and remineralization of tooth and initial carious lesion.

Keywords: functional property; glass-ionomer cement; hydroxyapatite; mechanical property; reinforcement.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Figures

Figure 1
Figure 1
Surface pH of specimens during setting (t-test–* p < 0.05, ** p < 0.01, *** p < 0.001).
Figure 2
Figure 2
Surface pH of specimens after setting (t-test–* p < 0.05, ** p < 0.01, *** p < 0.001). w: week/weeks.
Figure 3
Figure 3
Changes in pH of lactic acid with immersed samples that were stored for one week after the start of cement mixing. Different letters indicate significant differences (t-test–p < 0.05). There were no significant differences between the values after 60 min immersion.
See this image and copyright information in PMC

References

    1. Paddick J.S., Brailsford S.R., Kidd E.A.M., Beighton D. Phenotypic and genotypic selection of microbiota surviving under dental restorations. Appl. Environ. Microbiol. 2005;71:2467–2472. doi: 10.1128/AEM.71.5.2467-2472.2005. - DOI - PMC - PubMed
    1. FDI World Dental Federation FDI policy statement on Minimal Intervention Dentistry (MID) for managing dental caries. Int. Dent. J. 2017;67:6–7. doi: 10.1111/idj.12308. - DOI - PMC - PubMed
    1. Frencken J.E., Peters M.C., Manton D.J., Leal S.C., Gordan V.V., Edan E. Minimal intervention dentistry (MID) for managing dental caries—A review. Int. Dent. J. 2012;62:223–243. doi: 10.1111/idj.12007. - DOI - PMC - PubMed
    1. Splieth C.H. Revolutions in Pediatric Dentistry. Quintessence Publishing; London, UK: 2011. pp. 152–153.
    1. Pitts N.B., Baez R.J., Diaz-Guallory C., Donly K.J., Alberto-Feldens C., McGrath C., Phantumvanit P., Seow W.K., Sharkov N., Songpaisan Y., et al. Early childhood caries: IAPD Bangkok Declaration. Int. J. Paediatr. Dent. 2019;29:384–386. - PubMed

LinkOut - more resources