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. 2019 Dec 7;7(1):69.
doi: 10.1186/s40635-019-0280-z.

Report of the first AKI Round Table meeting: an initiative of the ESICM AKI Section

M Ostermann  1 , A Schneider  2 , T Rimmele  3 , I Bobek  4 , M van Dam  5 , M Darmon  6 , L Forni  7 , O Joannes-Boyau  8 , M Joannidis  9 , M Legrand  10 , J Prowle  11 , A Zarbock  12 , E Hoste  13   14
Affiliations

Report of the first AKI Round Table meeting: an initiative of the ESICM AKI Section

M Ostermann et al. Intensive Care Med Exp. .

Abstract

Purpose: Critical Care Nephrology is an emerging sub-specialty of Critical Care. Despite increasing awareness about the serious impact of acute kidney injury (AKI) and renal replacement therapy (RRT), important knowledge gaps persist. This report represents a summary of a 1-day meeting of the AKI section of the European Society of Intensive Care Medicine (ESICM) identifying priorities for future AKI research.

Methods: International Members of the AKI section of the ESICM were selected and allocated to one of three subgroups: "AKI diagnosis and evaluation", "Medical management of AKI" and "Renal Replacement Therapy for AKI." Using a modified Delphi methodology, each group identified knowledge gaps and developed potential proposals for future collaborative research.

Results: The following key research projects were developed: Systematic reviews: (a) epidemiology of AKI with stratification by patient cohorts and diagnostic criteria; (b) role of higher blood pressure targets in patients with hypertension admitted to the Intensive Care Unit, and (c) specific clearance characteristics of different modalities of continuous renal replacement therapy (CRRT). Observational studies: (a) epidemiology of critically ill patients according to AKI duration, and (b) current clinical practice of CRRT. Intervention studies:( a) Comparison of different blood pressure targets in critically ill patients with hypertension, and (b) comparison of clearance of solutes with various molecular weights between different CRRT modalities.

Conclusion: Consensus was reached on a future research agenda for the AKI section of the ESICM.

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Conflict of interest statement

AS has received speaker honoraria from Fresenius Medical Care, B Braun Avitum and Cytosorbents SA. EH has received speaker’s fees from Alexion, Sopachem and Astute Medical, and travel support from AM Pharma. MJ has received honoraria and research support from Baxter Healthcare Corp, AM Pharma, CLS Behring, Fresenius and Astute Medical. ML has received lecture fees from Baxter and Fresenius Medical, research support from Sphingotech and consulting fees from Novartis. MO has received speaker honoraria and research funding from Fresenius Medical Care and Baxter.

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