Confirmed causal effect of obesity on asthma and new insights on potential underlying shared genetic mechanisms

Affiliations

¹ MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom. Electronic address: Raquel.Granell@bristol.ac.uk.
² MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

Editorial

Raquel Granell et al. J Allergy Clin Immunol. 2020 Feb.

. 2020 Feb;145(2):484-486.

doi: 10.1016/j.jaci.2019.11.033. Epub 2019 Dec 6.

¹ MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom. Electronic address: Raquel.Granell@bristol.ac.uk.
² MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

No abstract available

Keywords: Obesity; asthma; cross-trait genome-wide association study; gene expression; shared genetics.

Comment on

Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.
Zhu Z, Guo Y, Shi H, Liu CL, Panganiban RA, Chung W, O'Connor LJ, Himes BE, Gazal S, Hasegawa K, Camargo CA Jr, Qi L, Moffatt MF, Hu FB, Lu Q, Cookson WOC, Liang L. Zhu Z, et al. J Allergy Clin Immunol. 2020 Feb;145(2):537-549. doi: 10.1016/j.jaci.2019.09.035. Epub 2019 Oct 24. J Allergy Clin Immunol. 2020. PMID: 31669095 Free PMC article.