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Observational Study
. 2020 Feb:38:101867.
doi: 10.1016/j.msard.2019.101867. Epub 2019 Nov 23.

Cesarean section in women with MS: A choice or a need?

De Giglio L  1 , Federici S  2 , Ruggieri S  3 , Borriello G  4 , D'Errico Ma  5 , De Angelis C  5 , Pozzilli C  6
Affiliations
Observational Study

Cesarean section in women with MS: A choice or a need?

De Giglio L et al. Mult Scler Relat Disord. 2020 Feb.

Abstract

A multidisciplinary approach is needed for the management of pregnancy related issues in women affected by Multiple Sclerosis, however little attention has been devoted to the modality of delivery. Here we aimed to investigate whether the diagnosis of multiple sclerosis (MS) influences delivery modality in MS patients. Patients who received the diagnosis before pregnancy showed a lower frequency of natural delivery and a higher frequency of both planned and urgency caesarean sections. Gestational weeks and birth weight were lower in MS patients when compared with healthy subjects. The diagnosis of MS may drive the decision of the gynaecologist to perform a caesarean delivery.

Keywords: Childbirth; Delivery modality; Multiple sclerosis; Obstetric risk; Pregnancy; cesarean section.

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Conflict of interest statement

Declaration of Competing Interest SF, CDA have nothing to disclose; LDG received speaking onoraria from Genzyme and Novartis, travel grant from Biogen, Merk, Teva, consulting fee from Genzyme, Merk and Novartis; SR received fee as speaking honoraria from Teva, Merck Serono, Biogen, travel grant from Biogen, Merck Serono, fee as advisory board consultant from Merck Serono and Novartis; GB received consulting and lecture fees and travel grants from Almirall, Bayer, Biogen, Genzyme, Merck Serono, Novartis, Roche and Teva; CP received consulting and lecture fees and research funding and travel grants from Almirall, Bayer, Biogen, Genzyme, Merck Serono, Novartis, Roche and Tevareceived consulting and lecture fees and research funding and travel grants from Almirall, Bayer, Biogen, Genzyme, Merck Serono, Novartis, Roche and Teva