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Comparative Study
. 2020 Mar;36(3):176-179.
doi: 10.1089/AID.2019.0220. Epub 2020 Jan 6.

Short Communication: Comparison of Calculated Low-Density Lipoprotein Cholesterol (LDL-C) Values in HIV-Infected and HIV-Uninfected Men Using the Traditional Friedewald and the Novel Martin-Hopkins LDL-C Equations

Edward E Schneider  1 , Sudipa Sarkar  2 , Joseph B Margolick  1 , Seth S Martin  3 , Wendy S Post  3 , Todd T Brown  2
Affiliations
Comparative Study

Short Communication: Comparison of Calculated Low-Density Lipoprotein Cholesterol (LDL-C) Values in HIV-Infected and HIV-Uninfected Men Using the Traditional Friedewald and the Novel Martin-Hopkins LDL-C Equations

Edward E Schneider et al. AIDS Res Hum Retroviruses. 2020 Mar.

Abstract

The Martin-Hopkins equation used to calculate low-density lipoprotein cholesterol (LDL-C) is more accurate than the traditional Friedewald equation, especially at higher triglyceride levels, which are more common in people with HIV (PWH). Thus, using LDL-C values calculated by the Martin-Hopkins equation may improve clinical care of PWH.

Keywords: HIV; LDL-C; Martin–Hopkins LDL-C equation; hypertriglyceridemia; low-density lipoprotein cholesterol.

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Conflict of interest statement

No competing financial interests exist.

Figures

FIG. 1.
FIG. 1.
Difference in LDL-C values as calculated by Martin–Hopkins and Friedewald equations (LDL-CMH − LDL-CF) in relation to triglyceride levels and HIV status. LDL-C, low-density lipoprotein cholesterol.
See this image and copyright information in PMC

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