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Review
. 2020 Mar;14(3):183-197.
doi: 10.1111/crj.13129. Epub 2020 Jan 21.

Risk factors of chronic obstructive pulmonary disease exacerbations

Stanca-Patricia Hogea  1 , Emanuela Tudorache  1 , Ariadna Petronela Fildan  2 , Ovidiu Fira-Mladinescu  1 , Monica Marc  1 , Cristian Oancea  1
Affiliations
Review

Risk factors of chronic obstructive pulmonary disease exacerbations

Stanca-Patricia Hogea et al. Clin Respir J. 2020 Mar.

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory disease characterised by persistent respiratory symptoms and airflow limitation. COPD has a major impact on public health, mainly because of its increasing prevalence, morbidity and mortality. The natural course of COPD is aggravated by episodes of respiratory symptom worsening termed exacerbations that contribute to disease progression. Acute Exacerbations of COPD (AECOPD) can be triggered by a multitude of different factors, including respiratory tract infections, various exposures, prior exacerbations, non-adherence to treatment and associated comorbidities. AECOPD are associated with an inexorable decline of lung function and a significantly worse survival outcome. This review will summarise the most important aspects regarding the impact of different factors that contribute to COPD exacerbations.

Keywords: bronchiectasis; microorganisms; spirometry.

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References

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