Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Dec 8;12(12):e231296.
doi: 10.1136/bcr-2019-231296.

Importance of clinical tests in ocular myasthenia

Affiliations
Case Reports

Importance of clinical tests in ocular myasthenia

Gunjan Saluja et al. BMJ Case Rep. .

Abstract

A 24-year-old otherwise healthy male presented to us with unilateral ptosis and contralateral lid retraction with limitation of extraocular movements; the disease had a gradual chronic course, which raised a suspicion of ocular myasthenia. Ice pack test was performed, which improved the ptosis; further investigations confirmed the diagnosis of ocular myasthenia. Patient was started on pyridostigmine and oral prednisolone which improved the extraocular movements and ptosis.

Keywords: motor neurone disease; muscle disease.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Clinical presentation of the patient. Note the unilateral ptosis and contralateral lid retraction.
Figure 2
Figure 2
Note the exo-deviation and limitation of extraocular movements.
Figure 3
Figure 3
Ice pack test.
Figure 4
Figure 4
Neostigmine test. Note the improvement of ptosis after the administration of neostigmine.

References

    1. Peragallo JH, Velez FG, Demer JL, et al. . Long-term follow-up of strabismus surgery for patients with ocular myasthenia gravis. J Neuroophthalmol 2013;33:40–4. 10.1097/WNO.0b013e318280d630 - DOI - PMC - PubMed
    1. Grigg J. Extraocular muscles: relationship of structure and function to disease. Aust N Z J Ophthalmol 1999;27:369–70. 10.1046/j.1440-1606.1999.00253.x - DOI - PubMed
    1. Barton JJ, Fouladvand M. Ocular aspects of myasthenia gravis. Semin Neurol 2000;20:7–20. 10.1055/s-2000-6829 - DOI - PubMed
    1. Singman EL, Matta NS, Silbert DI. Use of the Cogan lid twitch to identify myasthenia gravis. J Neuroophthalmol 2011;31:239–40. 10.1097/WNO.0b013e3182224b92 - DOI - PubMed
    1. Mee J, Paine M, Byrne E, et al. . Immunotherapy of ocular myasthenia gravis reduces conversion to generalized myasthenia gravis. J Neuroophthalmol 2003;23:251–5. 10.1097/00041327-200312000-00002 - DOI - PubMed