Molecular glue concept solidifies

Affiliations

¹ Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.
² Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany. schulman@biochem.mpg.de.

Comment

Kheewoong Baek et al. Nat Chem Biol. 2020 Jan.

. 2020 Jan;16(1):2-3.

doi: 10.1038/s41589-019-0414-3.

¹ Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.
² Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany. schulman@biochem.mpg.de.

No abstract available

Comment on

Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15.
Faust TB, Yoon H, Nowak RP, Donovan KA, Li Z, Cai Q, Eleuteri NA, Zhang T, Gray NS, Fischer ES. Faust TB, et al. Nat Chem Biol. 2020 Jan;16(1):7-14. doi: 10.1038/s41589-019-0378-3. Epub 2019 Nov 4. Nat Chem Biol. 2020. PMID: 31686031 Free PMC article.
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Bussiere DE, Xie L, Srinivas H, Shu W, Burke A, Be C, Zhao J, Godbole A, King D, Karki RG, Hornak V, Xu F, Cobb J, Carte N, Frank AO, Frommlet A, Graff P, Knapp M, Fazal A, Okram B, Jiang S, Michellys PY, Beckwith R, Voshol H, Wiesmann C, Solomon JM, Paulk J. Bussiere DE, et al. Nat Chem Biol. 2020 Jan;16(1):15-23. doi: 10.1038/s41589-019-0411-6. Epub 2019 Dec 9. Nat Chem Biol. 2020. PMID: 31819272

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