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. 2019;108(16):1097-1099.
doi: 10.1024/1661-8157/a003340.

[A Sweet Drink with Consequences]

[Article in German]
Affiliations

[A Sweet Drink with Consequences]

[Article in German]
Beatriz Noronha et al. Praxis (Bern 1994). 2019.

Abstract

A Sweet Drink with Consequences Abstract. Intoxications with ethylene glycol are rare, however, small quantities from the substance can be life-threatening. Regarding the treatment it is important to recognize the intoxication quickly and to immediately start the appropriate treatment. Intoxications with ethylene glycol or with methanol should always be considered as differential diagnosis in patients with severe metabolic acidosis. It is also very important to calculate the osmolal gap.

Zusammenfassung. Vergiftungen mit Ethylenglykol sind selten, jedoch führt bereits eine geringe eingenommene Menge der Substanz zu Toxizität. Die Schlüsselrolle in der Behandlung liegt im raschen Erkennen einer Intoxikation sowie der sofortigen und gezielten Therapie. Differenzialdiagnostisch sollte man bei Patienten mit einer schweren metabolischen Azidose eine Vergiftung mit Ethylenglykol oder Methanol immer ausschliessen. Dies gelingt nicht zuletzt dank der Berechnung der osmolaren Lücke.

Keywords: Ethylene glycol intoxication; Ethylenglykolintoxikation; Fomepizol; Frostschutzmittel; antifreeze; fomepizole; metabolic acidosis; metabolische Azidose; osmolal gap; osmolare Lücke.

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