Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1977;56(3):255-8.
doi: 10.1016/0305-0491(77)90010-4.

Bilirubin metabolism in the spiny dogfish, Squalus acanthias, and the small skate, Raja erinacea

P L Jansen  1 , I M Arias
Affiliations
Comparative Study

Bilirubin metabolism in the spiny dogfish, Squalus acanthias, and the small skate, Raja erinacea

P L Jansen et al. Comp Biochem Physiol B. 1977.

Abstract

1. The main bilirubin conjugate in bile of spiny dogfish (Squalus Acanthias) and small skate (Raja Erinacea) is bilirubin monoglucuronide. 2. Microsomal preparations from dogfish and small skate liver have similar bilirubin UDPglucuronyltransferase (UDPGT) activity and catalyze the conjugation of bilirubin with glucose from UDPglucose. 3. The activity of bilirubin glucosidation (UDPGT) was 0.5 times UDPG1T activity in dogfish and 0.15 times in skate liver microsomes. 4. Sodium cholate increased UDPGT and UDPG1T activities in dogfish and skate liver microsomal preparations only minimally, but the detergent markedly increased thermolability of UDPGT in skate liver microsomes.

PubMed Disclaimer

Publication types